Pesquisa sobre:
PROTEIN KINASE C-ALPHA
Descritores Encontrados:
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DeCS
Descritor
Inglês
:
Protein Kinase C-alpha
Descritor
Espanhol
:
Proteína Quinasa C-alfa
Descritor
Português
:
Proteína Quinase C-alfa
Sinônimos
Inglês
:
PKC-alpha Serine-Threonine Kinase
Categoria:
D08.811.913.696.620.682.700.725.100
Definição
Inglês
:
A cytoplasmic
serine
threonine
kinase involved in regulating
CELL DIFFERENTIATION
and CELLULAR PROLIFERATION. Overexpression of this enzyme has been shown to promote
PHOSPHORYLATION
of BCL-2
PROTO-ONCOGENE PROTEINS
and chemoresistance in human acute
leukemia
cells.
Nota Histórica
Inglês
:
2006(1999)
Qualificadores Permitidos
Inglês
:
AD
administration & dosage
AE
adverse effects
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DU
diagnostic use
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Número do Registro:
50721
Identificador Único:
D051571
Ocorrência na BVS
:
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CID-10
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